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Anti Aquaporin 4 Antibody. Following antigen retrieval using sodium citrate h.i.e.r. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications.
antiAquaporin 4 antibody Product No. ABIN2852688 from www.antibodies-online.com
Nmo is a unique disease ideal for monoclonal antibody blocker therapy because the single target of pathogenic autoantibodies, aqp4, is a plasma membrane protein having a small extracellular footprint compared to antibody size, and pathology is dependent on antibody effector function. Optimal working dilutions must be determined by end user. 1:500 on rat brain membranes.
The Antibody Can Be Used In Western Blot, Immunohistochemistry, And Immunocytochemistry Applications.
Evaluated by western blotting in mouse heart tissue lysate. Nmo is a unique disease ideal for monoclonal antibody blocker therapy because the single target of pathogenic autoantibodies, aqp4, is a plasma membrane protein having a small extracellular footprint compared to antibody size, and pathology is dependent on antibody effector function. Optimal working dilutions must be determined by end user.
Nmo Causes Optic Neuritis And Transverse Myelitis.
Mouse kidney tissue lysate lane 3 : Dilutions should be made using a. A previous lot of this antibody was used on rat brain sections.
1:500 On Rat Brain Membranes.
Buy rabbit polyclonal antibody to aquaporin 4 (a54118). Evaluated by western blotting in mouse heart tissue lysate. Aqp4 antibody (4/18) is a high quality monoclonal aqp4 antibody (also designated aquaporin 4 antibody) suitable for the detection of the aqp4 protein of mouse, rat and human origin.
Centrifuge Antibody Preparation Before Use (10,000 X G For 5 Min).
86/100, based on 1 pubmed citations. Early discrimination between ms and nmo is important, as optimum treatment for both. Home > search results > abcam > anti aquaporin 4 aqp4 249 323 antibody.
The Binding Sites Of This Autoantibody Were Reported To Colocalize With Aquaporin 4 (Aqp4) Water Channels.
928502), the tissue was incubated with 5.0 µg/ml of the primary antibody overnight at 4°c. It is expressed predominantly in the mature brain, but also in the eye, kidney, intestine and lung. Rat stomach tissue lysate lane 4 :
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